*Dr. Keerthana N., PG Scholar, Dept. of Dravyaguna, ALNRMAMC, Koppa
Prof. (Dr.) Sanjaya K.S., Dept. of Dravyaguna, ALNRMAMC, Koppa
*Corresponding Author: [email protected]
Received: 30-05-2020 Corrected Received: 22-08-2020 Accepted: 12-09-20
Abstract: Background: Increasing burden of antimicrobial resistant against few of antibiotics is matter of concerns for healthcare professionals and common people across the globe. Medicines of natural sources may be the options for such resistance by various way. Plants rich in volatile oil have shown antibacterial activities. Leucas species from Lamiaceae family reported with bactericidal activities. Some compounds of volatile oil of different species of Leucas are common as caryophyllene etc. These compounds have already been investigated for inhibitory actions against bacteria.
Leucas cephalotes: The hexane and methanol extract of leaves of Leucas cephalotes against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa have been shown in one study while another details about the action specified with Gram-positive and Gram-negative bacteria separately.
Leucas aspera: Root extract of Leucas aspera has exhibited highest inhibition in comparison to all extracts followed by flower extracts. It was more active against Salmonella species.
Leucas zeylanica: A study shows the inhibitory effects of methanolic extract of whole plant of Leucas zeylanica against three Gram-positive and two Gram-native bacteria with significant inhibitory effects.
Discussion and Conclusion: Studies report maximum percentage of â-caryophyllene in L. aspera with greater percentage of caryophyllene oxide in L. cephalotes. A study shows weak to moderate inhibitory action of Staphylococcus aureus, Escherichia coli, Salmonella typhimurium and Enterococcus faecallis. Compounds of these plants may have synergistic effects while working against different strains of bacteria.
Key words: Antibacterial, Leucas cephalotes, Leucas aspera, Leucas zeylanica, Volatile oil, Caryophyllene…….