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Survival benefits of parental care is well known fact among the mammalians including human beings. Effects of such care is observed with both genetic and epigenetic changes through the generations. The degree of care and impacts of parental genes have resulted in various levels of outcomes. Charak Samhita Sarirasthana 6/13 mentions the possibility of strength in child, if birth takes place in house of strong persons, an indication of genetic relationships. Parental care is associated with family income, education, social status and occupational backgrounds of parents, an immediate environment for any child. Charak Samhita Sarirasthana 1/147 endorses on impacts of immediate environment indicating the coming forth of memory being in touch with intellects. Recently, a research published in D...

       ‘Diet as key contributor for brain health’ is shown in one of article published in Neurology on 5th October. The study is mainly restricted to Omega-3 fatty acids consumptions and their neurological outcomes (Satizabal et al.). Cross-sectional investigation of red blood cell (RBC) Omega 3-fatty acid concentration was investigated. Omega-3 fatty acid index is used to measure the amount of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Gas chromatography was used to measure Omega-3 index. The apolipoprotein E (APOE) genotype was used to examine the cognitive outcome. The study observes Omega-3 index association with better brain cognitive function in middle-aged of people. Earlier study by Harris and Schacy (2004) has shown the relationship of the Omega-3 index with decre...

             A work published in The Lancet dated on 29th August 2022 reveals the muscle pain and weakness after statin treatment for atherosclerotic cardiovascular disease. Other studies mention various pathways for effects of statin on musculoskeletal system leading to muscle pain. Pathways include ubiquitin proteasome pathway, impaired signal transduction, abnormal fat oxidation, proteolysis, reduction in Q10 coenzyme etc. Lipid lowering effects of statin also affects peripheral nerves leading to muscle pain. Affects come in terms of disruption or disorganization of lipids of endoneurium and perineurium. These lipids are rich in linoleic acid, an important composition of sesame oil (Tila taila). Linoleic acid (n-6 PUFA) also reduces the risks of coronary heart diseases by bringing the f...

Human beings are inherently and intensely social for their needs of survival. In many cases, people feel disconnectedness or isolated either being with others or being socially isolated. Such feelings are known as loneliness. The effects of loneliness on neural chemistry have been proven. A study published in Journal of American Heart Association on 4th August reveals the association of cardiovascular diseases and brain health with social isolation and loneliness. Due to behavioural, psychological and physiological changes, health of heart and brain get affected. Study notes the prevalence of coronary heart disease (CHD) and stroke in those who are socially isolated or lonely. The study has taken the reference of both objective and perceived (subjective) isolation. Various other studies s...

People without perception of smell is known to be devoid of life as mentioned in Charak Indriyasthana 4/21. Does it indicate death or it is merely taken for inability to enjoy life? The Hindu, 24th March 2021 highlighted a case of chef who lost her sense of smell 30 years before, but still enjoying her life. Rare cases of congenital anosmia are also reported in Kallmann syndrome and Bardet-Biedl syndrome (BBS). Life-expectancy is not affected in Kallmann syndrome, whereas 25% people of BBS die before 44 years as noted by O’dea et al. (1996). Miyamoto and others (2010) revealed the olfactory dysfunction (including anosmia) in idiopathic rapid eye movement sleep behavior disorder. Olfactory dysfunction is connected to hindrance of odorants reaching to olfactory receptors in olfactory epithe...