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Editorial-April

Editorial-April

Editorial
Time demands the fight against the different variants of COVID-19. Antibodies are only observed as solutions by scientists. Vaccines were expected one step ahead in these regards. A new study published in Nature on 8th March revealed the escaping nature of new variants (UK and South Africa) of COVID-19 virus against vaccines of Moderna or Pfizer. Recently generated variant of Brazil is not studied. Mutations in virus may divert the signaling pattern of antibodies generated after vaccination. So, the most important part is breaking the link for spreading the mutations. Still, studies are required to cross the changes in responses of individual physiological bodies against COVID-19 and its variants. Differing responses are related to genes and, genetic impacts are already studied as core fa...
Standard Operating Procedures For Manufacturing and Analysis of Masha Taila

Standard Operating Procedures For Manufacturing and Analysis of Masha Taila

Articles
*Prof. (Dr.) Milind Hukkeri, Dept. RS&BK, ALNRMAMC, KoppaAnushree H.S., Research Associate, Quality Control Lab., ALNRMAMC, KoppaProf. (Dr.) Dinesh Kumar Mishra, HOD, Dept. RS&BK, ALNRMAMC, Koppa *Corresponding Author: dr.milindhukkeri@yahoo.inPaper Received: 21-01-2021 Paper Accepted: 05-02-2021 Corrected: 16-02-21 Abstract: Background: Standard operating procedures (SOPs) are step by step instructions to achieve uniformity of efficacy and quality. It is becoming mandatory for pharmaceutical industries as the drugs are part of everyone’s life. Ayurvedic pharmaceutical classical texts deal with various types of formulation preparation techniques in written forms. The steps are mentioned based on resources of that time. No complete details based on quality measurements including ti...
Editorial- March

Editorial- March

Editorial
The precarious condition generated after deteriorating climate is alarming. Many of diseases are linked with different types of pollutions. Air pollution is one of dangerous factor connected with different types diseases of respiratory and other systems.Recently, International Journal of Obesity reported in one of articles about association of early exposure to air pollution to obesity in children. In a longitudinal study of Spain including 416,955 children, 34.2% developed obesity. A strong association was observed with exposure to NO2, PM10, and PMcoarse. A more specific study is reported in Nature Scientific Reports displaying the pathological impacts of specific parameters on health. Researchers studied Hispanic group of children (6-8 years) in California exposed to 1 day- 12 month av...
Editorial- February

Editorial- February

Editorial
Death is inevitable and it is certain. It becomes powerful gift, once anyone is able to save others’ life by donating organs after death. Manusmriti clearly mentions donations as sacred approach and among donations, donation of own body as infinitely worthwhile. Donation of organs is need of time as many people die due to organ failures or, many of organs face decline in quality after death before transplantation. The process of transplantation of organs is needed to be very quick after death. Declaration of death becomes important as waiting too long brings decline in quality of organs. Recently on January 28, in issue of The New England Journal of Medicine, Dhanani et al. collected data of 631 patients from 20 intensive care units from three countries for an observational study to ascer...
A Clinical Evaluation of Lodhradhanyvacha Lepa on Mild and Moderate Acne vulgaris (Youvana Pidaka)

A Clinical Evaluation of Lodhradhanyvacha Lepa on Mild and Moderate Acne vulgaris (Youvana Pidaka)

Articles
A Clinical Evaluation of Lodhradhanyakvachadi Lepa on Mild and Moderate Acne vulgaris (Youvana Pidaka)*Dr. Jagadish Handiganur, Prapti Clinic, Hubballi, Karnataka*Corresponding Author: jagadishhe@gmail.comPaper Received: 21-09-2020 Paper Accepted: 02-11-2020 Corrected: 15-12-20 Abstract: Background: Acne is one most prevalent and common problem affecting 95% of adolescents. It is small elevated inflamed or non-inflamed bumps with blackheads, whiteheads, papules, pustules, cysts or nodules depending upon the severity index. The pathogenesis includes involvement of sebaceous glands, hormones, conrneocytes, keratinization and inflammatory responses. Drugs used in treatment works usually on different aspects to control inflammation and microbial growth along with wound healing properties. In ...
A Clinical Evaluation of Ashwagandha Churna on Short-term Insomnia

A Clinical Evaluation of Ashwagandha Churna on Short-term Insomnia

Articles
*Dr. Aby Mathew, PG Scholar, ALNRMAMC, Koppa, KarnatakaDr. Akhila Vinod, PG Scholar, ALNRMAMC, Koppa, Karnataka*Corresponding Author: abym2343.am@gmail.comPaper Received: 15-09-2020 Paper Accepted: 13-10-2020 Corrected: 28-11-20 Abstract: Background: Ayurveda considers sleep as one of important sub-pillars of body associated with strength, potency, intellect etc. Diagnostic and Statistical Manual of Mental Disorders (DSM-V) refers dissatisfaction with sleep quantity and quality to insomnia. International Classification of Sleep Disorders (ICSD) 3 has classified insomnia in acute or short-term insomnia and chronic insomnia. Charak Chikitsasthana 24/88-91 mentions exhausted mind, sense organs, grief, alcohol etc. as various causes of insomnia. Various treatments are suggested in Ayurveda as...
Editorial- January

Editorial- January

Editorial
Centers for Disease Control and Prevention (CDC) considers prediabetes as serious condition. It is a state of intermediate hyperglycemia where sugar level is higher than normal, but not enough high to diagnose as type 2 diabetes. Recently, a research work published in Nature Medicine identifies six sub-phenotypes for prediabetes through a cohort study. The 25 years long study included 7,000 participants from Germany and UK. The study was led by Professor Hans-Urlich Haring. The study used partitioning of variables using glucose tolerance tests, MRI-measured body fat distribution, liver fat content and genetic risk. Six different clusters of sub-phenotypes were categorized as cluster 1 to 6. Three of these clusters i.e., 1,2 and 4 are suggested to be with low risk diabetes. Participants of...
Pharmacognostical Evaluation of Stem of Costus speciosus (J.Koenig) Smith.

Pharmacognostical Evaluation of Stem of Costus speciosus (J.Koenig) Smith.

Articles
*Dr. Manjiri M. Kulkarni, Professor, Dept. of Dravyaguna, MES Ayurved Mahavidylaya, Lote, Khed, RatnagiriAnushree H.S., Quality Control Laboratories, ALNRMAMC, Koppa,  Karnataka*Corresponding Author: kulkarnimm912@gmail.comPaper Received: 28-08-2019  Paper Accepted: 21-09-2020  Corrected: 11-11-20 Abstract: Background: Costus speciosus (J. Koenig) Smith. or Kebuka is known for use of rhizome in various problems including cough, rheumatism etc. However, other parts are also used. The stem is used in fever, dysentery etc. It is reported with saponins, steroids, flavonoids etc.Materials and Methods: Macroscopic and microscopy were done. Photomicrographs were taken for transverse section of stem and powder of stem. Physicochemical analysis included the pharmacopoeial standards mentioned with ...
Editorial- December

Editorial- December

Editorial
A recent study published online on 9th December in Nature Communications by Peckham et al. (2020) shows gender based development of severity of COVID-19 subjected to ITU (intensive therapy unit). The study is based on meta-analysis of reports from 47 countries including 3,111,714 cases. However, study considers the equivalent risks of infection in both males and females, still it shows higher odds for males. The requirement of ITU and death is respectively observed 2.84 times higher and 1.39 times higher in males. Study highlights the differences between male and females for both innate and adaptive immune system. Earlier findings from number of animals including mammals have revealed the genetic and hormonal guidance behind the better immunity in females than male. Higher expression of T...